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  • [email protected], Team 239902









    Hello all,

    Welcome to our Folding Team thread.

    As many others around the globe, we want to join the fight against the conditions that still plague humanity such as Huntington's Disease,Alzheimer's,Cancer and many more. We as enthusiasts have the perfect gear that can really pack a punch and make very valuable contributions towards the [email protected] project. Of course it is not just up to us enthusiasts but to all that can spare the up time and contribute.


    What is "Folding"

    [email protected] (FAH or [email protected]) is a distributed computing project for disease research that simulates protein folding, computational drug design, and other types of molecular dynamics. As of today, the project is using the idle resources of personal computers owned by volunteers from all over the world. Thousands of people contribute to the success of this project.
    Source: https://foldingathome.org/about

    The [email protected] project (FAH) is dedicated to understanding protein folding, the diseases that result from protein misfolding and aggregation, and novel computational ways to develop new drugs in general. Here, we briefly describe our goals, what we are doing, and some highlights so far.

    A distributed computing project must not only run calculations on millions of PCs, but such projects must produce results, especially in the form of peer-reviewed publications, public lectures, and other ways that disseminate the results from FAH to the greater scientific community. In the sidebar, you will find links to our progress in different areas.

    WHAT IS PROTEIN FOLDING AND HOW IS IT RELATED TO DISEASE?

    Proteins are necklaces of amino acids, long chain molecules. They are the basis of how biology gets things done. As enzymes, they are the driving force behind all of the biochemical reactions that make biology work. As structural elements, they are the main constituent of our bones, muscles, hair, skin and blood vessels. As antibodies, they recognize invading elements and allow the immune system to get rid of the unwanted invaders. For these reasons, scientists have sequenced the human genome – the blueprint for all of the proteins in biology – but how can we understand what these proteins do and how they work?

    However, only knowing this sequence tells us little about what the protein does and how it does it. In order to carry out their function (e.g. as enzymes or antibodies), they must take on a particular shape, also known as a “fold.” Thus, proteins are truly amazing machines: before they do their work, they assemble themselves! This self-assembly is called “folding.”

    WHAT HAPPENS IF PROTEINS DON’T FOLD CORRECTLY?

    Diseases such as Alzheimer’s disease, Huntington’s disease, cystic fibrosis, BSE (Mad Cow disease), an inherited form of emphysema, and even many cancers are believed to result from protein misfolding. When proteins misfold, they can clump together (“aggregate”). These clumps can often gather in the brain, where they are believed to cause the symptoms of Mad Cow or Alzheimer’s disease.
    Source: https://foldingathome.org/diseases/

    However put it simply, you can download a small client on to your PC that downloads what is called a ''Work Unit'' which is essentially a pre-compiled package for your PC to work on. It will use the free resources on your machine to complete computational work, once complete this valuable data is sent back to Stanford University for their talented team to look at. The great thing about folding is not only does it help the human race but if you are of the competitive nature you will be happy to learn that you earn points for each Work Unit you complete, so if you want to be the best and beat all the rest then here is your chance to show your PC muscle !


    How to get going

    You can download the client from here: https://foldingathome.org/alternative-downloads/

    The client comes in many forms and supports Windows as well as a wide variety of Linux based platforms. When inputting the team you are folding for, be sure to enter in 239902

    Don't forget to get your Passkey!


    What is a passkey?

    The passkey, a new feature beginning with the v6.0 FAH client, is a unique identifier that ties your contributions directly to you (not just those with your username). The use of a passkey prevents others from cheating using your name. Obtain a passkey from our web site (see below), enter it when you configure the client, and the client and servers will do the rest. You should keep your passkey secret.
    What is the purpose of a passkey?


    A passkey uniquely identifies you as an individual donor and is associated with results that you have completed. Previously we did not have unique identifiers in [email protected] (usernames for example can be shared by many people). One main benefit of passkeys is that if someone cheats, we will not need to zero out the points of everyone with that username — only the offending party and those without passkeys.

    Perhaps more interestingly, we have introduced a new Quick Return Bonus (QRB) points program, which is tied to passkeys. To earn this bonus, you must use a passkey.

    Finally, the existence of passkeys opens up future possibility of displaying your individual credit and other information, rather than just by username, so use the same passkey for all clients.
    Where can I get a passkey?

    https://apps.foldingathome.org/passkey/create
    Note: The passkey request form is case sensitive.
    System requirements & supported GPU's

    It is worth noting that not all GPU's are supported, to find out if your GPU is on the supported list see HERE

    For further system requirements, See respectively : Windows, Linux, Mac


    Trouble getting or sending a Work Unit ?

    For anyone having trouble getting issues a Work Unit or having trouble sending a finished one back to Stanford, this can sometime be due to server issues at Stanfords end whereby the Assign/Accept servers are saturated or otherwise having issues.

    Luckily you can check on the Stanford servers status here : [email protected] Server Stats

    Sometimes exiting your folding client and re-starting it can help, but sometimes you just have to be patient for the Assign/Accept servers to be ready to serve you.
    Last edited by ENTERPRISE; 15-04-2020, 12:12 PM.
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  • #2
    How to get started, the basics


    If you have any questions, feel free to post them here and I'll do my best to answer them, this way others who have the same questions can find answers.


    ExtremeHW [email protected] Setup Guide – by axipher



    You can also refer to [email protected]'s own Quick-start guide



    Current Team Stats




    Check our team stats on [email protected]
    Check our team stats on EOC
    Last edited by axipher; 13-05-2020, 02:10 PM.
    Case
    Rosewill RSV-R4000
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    EVGA Nvidia GTX 1050 Ti
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    Seasonic Focus Plus Gold 550W
    Motherboard
    Asus Prime X570-Pro
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    AMD Ryzen 3600x
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    Corsair 3200 MHz CL16 32 GB (4 x 8GB)
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    Intel P660 M.2 512 GB NVME SSD (x2)
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    Seagate IronWolf 6TB (x6)
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    Fractal Design Meshify C
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    Seasonic Focus Plus Gold 750W
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    Asus Prime X470-Pro
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    AMD Ryzen 2600x
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    • #3
      What up axipher, long time

      As to me folding, maybe, have a lot of projects to finish, and folding under Debian can be finicky to configure on dual cards.

      Think I put up somewhere near 130m points for OCN. core a4 units on my Tis in Linux give close to 1.5mil PPD :]
      Router
      ASUS UFO thing (ac-5300, latest merlin, TrendMicro (JP) AiProtection, Skynet MAC spoofing and APT evading intelligent firewall shell script ;)
      CPU
      3900x 4550/4500 CCD0 1.3875v FCLK DIV1 1900MHz IF
      GPU
      EVGA GTX 1080ti FTW3 SLI 2025/5940MHz stock voltage
      Memory
      G.SKILL Flare X 3200c14 @ 3800MHz c16-16-16-16-32-50-24(FAW)-294(tRFC) GDM OFF 1T
      Storage
      970 Evo, WD Black 2TB, WD Blue 4TB & 6TB im leet
      PSU
      COOLERMASTER V1000 (Seasonic 80+ Gold)
      Cooling
      Anidées AI-AUREOLA 35cfm digital RGB fans x7
      Case
      Anidées AI CRYSTAL AR3
      Keyboard
      GMMK v2 full size (104) | Kailh Box Jade | WASD Cherry Blue o-ring | HyperX PBT Puddings ;)
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      LG 3440x1440 HDR10 300 nit 34
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      Ghetto banger ancient well used 2007 Logitech Z-2300 8
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      Custom Linux w conky ring meters, desktop cube, compiz-reloaded, Emerald themes etc. :P
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      • #4
        Originally posted by neurotix View Post
        What up axipher, long time

        As to me folding, maybe, have a lot of projects to finish, and folding under Debian can be finicky to configure on dual cards.

        Think I put up somewhere near 130m points for OCN. core a4 units on my Tis in Linux give close to 1.5mil PPD :]
        Glad to have you here, I'm in the same boat on my Ubuntu box, my Navi GPU just doesn't want to fold and CPU units are sparse right now.
        Case
        Rosewill RSV-R4000
        GPU
        EVGA Nvidia GTX 1050 Ti
        PSU
        Seasonic Focus Plus Gold 550W
        Motherboard
        Asus Prime X570-Pro
        CPU
        AMD Ryzen 3600x
        Memory
        Corsair 3200 MHz CL16 32 GB (4 x 8GB)
        Storage
        Intel P660 M.2 512 GB NVME SSD (x2)
        Storage
        Seagate IronWolf 6TB (x6)
        Case
        Fractal Design Meshify C
        PSU
        Seasonic Focus Plus Gold 750W
        Motherboard
        Asus Prime X470-Pro
        CPU
        AMD Ryzen 2600x
        Memory
        Corsair 3200 MHz CL16 32 GB (4 x 8GB)
        Storage
        Intel P660 M.2 1 TB NVME SSD
        GPU
        Sapphire AMD Navi 5700
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        • #5
          Originally posted by neurotix View Post
          What up axipher, long time

          As to me folding, maybe, have a lot of projects to finish, and folding under Debian can be finicky to configure on dual cards.

          Think I put up somewhere near 130m points for OCN. core a4 units on my Tis in Linux give close to 1.5mil PPD :]
          Welcome back

          I remember my folding days under Linux, I am trying to recall the distro I used, needless to say Folding is more challenging on Linux than Windows that is for sure.

          For me it is all about .......

          windows GIF
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          • #6
            Router
            ASUS UFO thing (ac-5300, latest merlin, TrendMicro (JP) AiProtection, Skynet MAC spoofing and APT evading intelligent firewall shell script ;)
            CPU
            3900x 4550/4500 CCD0 1.3875v FCLK DIV1 1900MHz IF
            GPU
            EVGA GTX 1080ti FTW3 SLI 2025/5940MHz stock voltage
            Memory
            G.SKILL Flare X 3200c14 @ 3800MHz c16-16-16-16-32-50-24(FAW)-294(tRFC) GDM OFF 1T
            Storage
            970 Evo, WD Black 2TB, WD Blue 4TB & 6TB im leet
            PSU
            COOLERMASTER V1000 (Seasonic 80+ Gold)
            Cooling
            Anidées AI-AUREOLA 35cfm digital RGB fans x7
            Case
            Anidées AI CRYSTAL AR3
            Keyboard
            GMMK v2 full size (104) | Kailh Box Jade | WASD Cherry Blue o-ring | HyperX PBT Puddings ;)
            Monitor
            LG 3440x1440 HDR10 300 nit 34
            Audio
            Ghetto banger ancient well used 2007 Logitech Z-2300 8
            Operating System
            Custom Linux w conky ring meters, desktop cube, compiz-reloaded, Emerald themes etc. :P
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            • #7
              Originally posted by neurotix View Post
              It looks like some form of RGB is going on there
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              Asrock X570 Aqua (Run 783/999)
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              Quadro 1800 (Placeholder for 3080Ti Upgrade)
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              32GB Gskill Trident Z @3800Mhz (16/16/17/16/32)
              PSU
              EVGA 1600 Watt Supernova P2
              Storage
              1x 500GB Seagate Firecuda PCIe Gen4 (M.2)
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              1x 1TB Seagate Firecuda PCIe Gen4 (M.2)
              Cooling
              Custom WC
              Monitor
              Acer Predator X34 (Ultrawide)
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              Be Quiet Dark Base Pro 900 V2
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              • #8
                Originally posted by neurotix View Post
                Is that a picture for ants???
                Case
                Rosewill RSV-R4000
                GPU
                EVGA Nvidia GTX 1050 Ti
                PSU
                Seasonic Focus Plus Gold 550W
                Motherboard
                Asus Prime X570-Pro
                CPU
                AMD Ryzen 3600x
                Memory
                Corsair 3200 MHz CL16 32 GB (4 x 8GB)
                Storage
                Intel P660 M.2 512 GB NVME SSD (x2)
                Storage
                Seagate IronWolf 6TB (x6)
                Case
                Fractal Design Meshify C
                PSU
                Seasonic Focus Plus Gold 750W
                Motherboard
                Asus Prime X470-Pro
                CPU
                AMD Ryzen 2600x
                Memory
                Corsair 3200 MHz CL16 32 GB (4 x 8GB)
                Storage
                Intel P660 M.2 1 TB NVME SSD
                GPU
                Sapphire AMD Navi 5700
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                • #9
                  Weird Ill reupload it

                  https://i.postimg.cc/sDR5jqWy/20200301-151927.jpg
                  Router
                  ASUS UFO thing (ac-5300, latest merlin, TrendMicro (JP) AiProtection, Skynet MAC spoofing and APT evading intelligent firewall shell script ;)
                  CPU
                  3900x 4550/4500 CCD0 1.3875v FCLK DIV1 1900MHz IF
                  GPU
                  EVGA GTX 1080ti FTW3 SLI 2025/5940MHz stock voltage
                  Memory
                  G.SKILL Flare X 3200c14 @ 3800MHz c16-16-16-16-32-50-24(FAW)-294(tRFC) GDM OFF 1T
                  Storage
                  970 Evo, WD Black 2TB, WD Blue 4TB & 6TB im leet
                  PSU
                  COOLERMASTER V1000 (Seasonic 80+ Gold)
                  Cooling
                  Anidées AI-AUREOLA 35cfm digital RGB fans x7
                  Case
                  Anidées AI CRYSTAL AR3
                  Keyboard
                  GMMK v2 full size (104) | Kailh Box Jade | WASD Cherry Blue o-ring | HyperX PBT Puddings ;)
                  Monitor
                  LG 3440x1440 HDR10 300 nit 34
                  Audio
                  Ghetto banger ancient well used 2007 Logitech Z-2300 8
                  Operating System
                  Custom Linux w conky ring meters, desktop cube, compiz-reloaded, Emerald themes etc. :P
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                  • #10


                    Music to my ears, keep it up guys ! Nice to see the the [email protected] stats pages are working again, still a little on and off but better than the ''Bad Gateway'' I kept getting lol.
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                    32GB Gskill Trident Z @3800Mhz (16/16/17/16/32)
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                    1x 500GB Seagate Firecuda PCIe Gen4 (M.2)
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                    Custom WC
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                    • #11
                      I'll definitely join in soon. I have [email protected] set up right now because Alex has a smug coworker because he got 88K points in a week. We got to 2.425M points in 3 days so a nice chunk will be added when I start folding for here. Bare in mind though, that's my RTX 2070 and Alexs 9900K + GTX 1080Ti and Alexs 2500K + GT1030. I'm averaging about 1.2M PPD for 10-14 hours a day.
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                      • #12
                        Andrew

                        Nice would love to have you with us and anyone else of course. Thus far I am just folding on my 2080Ti's, but right now due to the move the PC is in the bedroom, so it is not committed overnight (I can sleep with it, the better half cannot).
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                        CPU
                        AMD Ryzen 9 3950X (16 Core/32 Thread) @ 4525/4500/4500/4350 (1.36v)
                        Motherboard
                        Asrock X570 Aqua (Run 783/999)
                        GPU
                        Quadro 1800 (Placeholder for 3080Ti Upgrade)
                        Memory
                        32GB Gskill Trident Z @3800Mhz (16/16/17/16/32)
                        PSU
                        EVGA 1600 Watt Supernova P2
                        Storage
                        1x 500GB Seagate Firecuda PCIe Gen4 (M.2)
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                        1x 1TB Seagate Firecuda PCIe Gen4 (M.2)
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                        Custom WC
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                        Acer Predator X34 (Ultrawide)
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                        • #13
                          It is actually crazy how much better hardware is these days as well as the optimization they've been doing over the years for [email protected] There's another forum I'm in that gives out awards for getting to 1 million points. These days you can get 1 million points in a day or two with a year old mid-range GPU.
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                          EVGA RTX 2070
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                          Samsung 860 Evo 1TB
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                          • #14
                            Originally posted by Andrew View Post
                            It is actually crazy how much better hardware is these days as well as the optimization they've been doing over the years for [email protected] There's another forum I'm in that gives out awards for getting to 1 million points. These days you can get 1 million points in a day or two with a year old mid-range GPU.
                            For sure, hardware has excelled hugely since the day where 1million points was a huge thing.

                            We are certainly thinking of adding awards to the site but they will certainly be different from other sites so that they are more with the times.
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                            CPU
                            AMD Ryzen 9 3950X (16 Core/32 Thread) @ 4525/4500/4500/4350 (1.36v)
                            Motherboard
                            Asrock X570 Aqua (Run 783/999)
                            GPU
                            Quadro 1800 (Placeholder for 3080Ti Upgrade)
                            Memory
                            32GB Gskill Trident Z @3800Mhz (16/16/17/16/32)
                            PSU
                            EVGA 1600 Watt Supernova P2
                            Storage
                            1x 500GB Seagate Firecuda PCIe Gen4 (M.2)
                            Storage
                            1x 1TB Seagate Firecuda PCIe Gen4 (M.2)
                            Cooling
                            Custom WC
                            Monitor
                            Acer Predator X34 (Ultrawide)
                            Case
                            Be Quiet Dark Base Pro 900 V2
                            Operating System
                            Windows 10 Pro X64
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                            • #15


                              Yeet
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                              Ryzen 5 1600
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                              Asus Prime B350 Plus
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                              EVGA RTX 2070
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                              16GB Corsair (2x8GB)
                              Storage
                              Samsung 860 Evo 1TB
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                              Samsung 860 Evo 1TB
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                              Samsung 960 Evo 500GB
                              PSU
                              EVGA Supernova 650 G2
                              Keyboard
                              Ducky One2 Midnight MX Blue
                              Mouse
                              Steelseries Rival 310
                              Monitor
                              LG 49UM7400PLB
                              Monitor
                              Dell E207WFP
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                              Valve Index
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                              Windows 10 Pro
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                              Fractal Design Meshify C
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                              Thrustmaster T300RS
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