Come to find out, things are getting even tighter, you'll see in the next update. I was glad that I got that Zotac GPU because just about any other GPU would not have fit. The drive cage fans are massive about double the thickness of a standard fan so I have only a little bit past the PCIe slots.
Usually I will run my O/C at full boost all the time (all cores) and temps are managed based upon workload but this motherboard has an EPU feature that I'm going to look into and also see if I get the CPU stable with speedstep and power management enabled since it will be running 24x7. It makes the O/C a bit more challenging but I think I'll be fine since I'm targeting a modest 4Ghz.
https://www.asus.com/support/FAQ/1036401
I really like that case also and I had considered it. It reminds me a lot of a dell rack mount chassis and has a nice clean look to it. Rosewill is hit or miss but usually when they hit, they knock it out of the park.
I haven't really experienced storage over 10GB+ in my home lab, only 1GB (NFS) where it honestly wasn't very impressive. I am curious how well it would actually perform with benchmarks like ATTO over the wire. A lot of the used equipment like the EMC NS-120s are dog slow but tick all the checkboxes on paper. Good 10GB NICs are still $150.. We seem to be waaaay overdue for an industry standard bump to 10GB, it's still treated like it was just invented yesterday..
EDIT: I looked it up, the standard for 10GB ethernet was defined in 2002... 18 years ago... and only now are motherboards starting to ship with them standard. That's kind of interesting how network performance stayed stagnent for so long.